Immune System

Nutrition, intestinal health and immune system strongly depend on each other. Approx. 80 % of immune cells of the body are located in the intestine.

The nature as well as the function of the immune cells are influenced by the intestinal bacteria. Therefore, the type and the specific function of the immune cells, which migrate from the intestine into the body, depend very much on the constitution of the intestinal flora and thus also on the diet. It has already been shown in studies that the immune system can be influenced by changing the diet. In general, the immune system is divided into two main areas: one is the innate immune system and the other is the acquired immune system. The intestinal flora and its metabolic products have a high influence on both areas, but this is quite reciprocal.

One of the tasks of the immune system is to recognize and eliminate harmful and pathogenic bacteria as well as, for example, viruses and parasites in the intestine, whereas immune reactions have to be prevented against harmless and useful intestinal bacteria. For this reason, the immune system of the intestine must provide both inflammatory and anti-inflammatory mechanisms. Short-chain fatty acids have an effect on both areas. If insufficient short-chain fatty acids are present in the intestine, for example, the number of regulatory T cells, a subgroup of the white blood cells responsible for immune regulation, may also be low. In normal cases, these cells prevent the development of autoimmune diseases (e. g. psoriasis, neurodermatitis, types of rheumatism or multiple sclerosis) in healthy body, i. e. diseases in which the immune system reacts excessively and attacks its own body. Thereby this causes again inflammatory reactions in the body, which damage the tissue of, for example, the brain, lungs, joints or the pancreas. Short-chain fatty acids provide an "inflammation brake". An adequate supply of short-chain fatty acids helps the body to help itself or not to harm. Furthermore, there are important effects for metabolism and general intestinal health.

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The Human Gut: The Next Frontier for MS Therapies

25. August 2017

The next important therapy for patients with multiple sclerosis (MS), might not be a drug — it might be a microbe. Click here for the article Continue reading

Rumblings of Parkinson’s: Gut Microbiome Shifts in Early Stage of Disease

28. April 2017

By the time a person with Parkinson’s notices something is wrong, the microbes in his gut may have long known about it. Click here for the article Continue reading

#ACTRIMS2017 – Some Fatty Acids in Diet Help, Others Hurt Immune System, Study Reports

24. Februar 2017

Short-chain dietary fatty acids, such as propionate, drive the production of regulatory immune T-cells in patients with multiple sclerosis (MS), while long-chain acids promote T-cells that are involved in inflammatory... Continue reading

Statement: Administration of fatty acids of different chain lengths
How do you explain the regulatory mechanism of propionates?
Are immune cells still active or are they being down-regulated?
How do propionates work in autoimmune diseases and especially in allergies?
What is the mode of action of short-chain fatty acids, especially sodium propionate?
Is there a time restriction on the use?
Can the quality of life of MS patients be increased?
Is there any evidence for the use of sodium propionate?
What do these effects look like in particular?
What happens if you accidentally overdose?
What is included in Propicum?
What is sodium propionate?
Are there any positive effects on other diseases or healthy people?
How is the mode of action of short-chain fatty acids, especially sodium propionate?
Why is propionic acid interesting from a scientific point of view?
Is the intake in rheumatic diseases useful?
Is there a time restriction on the use?
Is there evidence of the use of sodium or calcium propionate?
Can the quality of life of MS patients be increased by taking sodium propionate?
Is there any evidence of the use of sodium propionate or calcium propionate?
How much sodium propionate should you consume daily?