Metabolism

The metabolism is the basis of all essential processes in our body.

Metabolism includes basically all biological and chemical processes occurring within our cells. The metabolism processes are needed for the preservation of the body, for energy generation and for the conservation of body functions. Short-chain fatty acids have an influence on several metabolic processes.

It is well-known that the intake of larger amounts of non-digestible plant fibers (i. e. high-fiber diet) favors weight loss and normalizes the metabolism of sugar. The blood glucose level decreases. At first, this seems somewhat contradictory because short-chain fatty acids, especially propionic acid, are used in the liver for glucosene generation (gluconeogenesis). But especially the propionic acid has a central role in this blood sugar regulation and influences favorably the metabolism of sugars at various points. In the intestine, for example, propionic acid is involved in the formation of sugar. This regulates the dietary intake and the sugar content, so we feel less desire for sweetness and the feeling of satiety is obtained faster. Specific cells of the pancreas (beta cells) can produce more insulin by short-chain fatty acids. Insulin is a hormone that reduces our sugar levels. A high insulin level also provides a stronger sense of satiety. Thus, short chain fatty acids affect our appetite.

Insulin is not the only hormone that can be increased through short-chain fatty acids. The release of gut hormones GLP-1 (glucagon-like peptide 1) and PYY (peptide-YY) is also increased. This has the effect that the sugar content is influenced positively, the stomach emptying is delayed and a feeling of satiety is obtained. The hormone PYY also has an appetite reducing effect. Short-chain fatty acids also use fats that do not need to be stored in the liver (fatty liver). In addition, the new formation of further fats, called triglycerides is reduced. These triglycerides are considered unfavorable and can lead to cardiovascular diseases. Furthermore, there are important effects for the immune system and general intestinal health.

News about Metabolism:

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Eating Fiber Might Help Prevent Osteoporosis

5. January 2018

Mention osteoporosis-preventing nutrients and most people will think of calcium and vitamin D, even though my colleague Dr. Dinerstein recently wrote they might not be effective in preventing fractures. Click here… Continue reading

Animal products, the microbiome, and heart disease

22. June 2016

Although steaks, hamburgers and all matter of red meat are popular menu fare, studies reveal red meat intake is associated with an elevated risk of cardiovascular disease and cardiovascular death.… Continue reading

An update on the link between short-chain fatty acids, diet, and human health

14. Juli 2016

A recent review, led by Dr Nuria Salazar from the Institute of Dairy Products of Asturias (Spain), belonging to the Spanish National Research Council, summarizes the up-to-date scientific evidence regarding… Continue reading

Statement: Sugar and fat metabolism
Statement: Nutrition and intake of propionates
How does the aktive mechanism of short-chain fatty acids, in praticular sodium propionate, works?
Is there a time restriction on the use?
Is there any evidence for the use of sodium propionate?
What happens if you accidentally overdose?
What is included in Propicum?
What is sodium propionate?
Should sodium / calcium propionate be taken with or independently of other food?
How is the mode of action of short-chain fatty acids, especially sodium propionate?
Why is propionic acid interesting from a scientific point of view?
Is there a time restriction on the use?
Is there evidence for the benefit of sodium or calcium propionate?
Is there any evidence of the use of sodium propionate or calcium propionate?
How much sodium propionate should you consume daily?